CJC-1295 DAC (5 mg) + Ipamorelin (5 mg) Stack

Research overview by Biohacking Elite · Last updated October 24, 2026
Research information notice

This page is provided for research and educational purposes only and does not provide medical advice, diagnosis, treatment recommendations, dosing instructions, or instructions for human use. Research findings should be interpreted within the population, model, formulation, route, outcomes, and study design reported by each cited source.

PEPTIDE STACKS

CJC-1295 DAC (5 mg) + Ipamorelin (5 mg) Stack

RESEARCH & EDUCATIONAL REFERENCE GUIDE

Research reference for CJC-1295 DAC and Ipamorelin, listed as separate 5 mg vials. Evidence on individual compounds should not be treated as proof of combined effects. For research and educational use only.

! For research and educational purposes only. Review all research information, limitations and references before interpretation.
NEUTRAL LABORATORY CALCULATIONS Use the Research Calculator for concentration, dilution and unit-conversion math. It does not provide or recommend a personal dose or administration schedule.
CJC-1295 DAC (5 mg) + Ipamorelin (5 mg) Stack
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Quick Reference

Alternate / Common Names
CJC-1295 DAC + Ipamorelin CJC DAC / Ipamorelin stack
Classification
Multi-vial growth-hormone secretagogue research stack
Vial / Reference Strength
CJC-1295 DAC 5 mg + Ipamorelin 5 mg (separate vials)
Product / Research Format
Two separate lyophilized peptide vials used as a research stack

What is CJC-1295 DAC (5 mg) + Ipamorelin (5 mg) Stack?

Research overview based on the cited scientific literature.

• Goal: Amplify endogenous GH/IGF-1 secretion through dual GHRH and ghrelin receptor pathways[5].

• Storage: Lyophilized frozen; reconstituted refrigerated; avoid repeated freeze-thaw cycles.

Storage Instructions

Proper storage preserves peptide integrity and efficacy.
• Lyophilized (dry powder): Store at ≤−15 °C (5 °F); preferably ≤−50 °C (−58 °F) for long-term storage[5].
• Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); use within 3–4 weeks[6].
• Allow vials to reach room temperature before opening to minimize condensation uptake.
• Avoid repeated freeze–thaw cycles of reconstituted solutions.

How is CJC-1295 DAC (5 mg) + Ipamorelin (5 mg) Stack studied?

CJC-1295 DAC functions as a synthetic GHRH analog that stimulates pituitary GH release. Its Drug Affinity Complex (DAC) moiety binds to serum albumin, extending its half-life to approximately 6–8 days and producing sustained, dose-dependent elevations in GH and IGF-1[1]. Ipamorelin is a selective growth hormone secretagogue that activates the ghrelin receptor (GHSR) to trigger rapid GH pulses without significantly affecting ACTH, cortisol, or prolactin[2]. When combined, these peptides act through complementary pathways—GHRH receptor and ghrelin receptor—to synergistically amplify endogenous GH secretion[3].

What does the research report about CJC-1295 DAC (5 mg) + Ipamorelin (5 mg) Stack?

Observations from preclinical and clinical literature on GH secretagogues.
• Body composition: GH secretagogues have demonstrated improvements in lean mass and reductions in fat mass in clinical studies[7].
• Sustained GH/IGF-1 elevation: CJC-1295 DAC produces prolonged elevations lasting 6–11 days per administration[1].
• Selectivity: Ipamorelin does not significantly increase cortisol or ACTH at therapeutic doses[2].
• Tolerability: Both peptides were well tolerated in human studies, with transient injection-site reactions being the most common adverse effect[8].
• Water retention, mild headache, and transient numbness/tingling have been reported with GH-elevating compounds.

Important Note

This content is provided for scientific research and educational purposes only. It does not provide medical advice, diagnosis, treatment, dosing, or administration instructions. The compounds discussed may be investigational and are not presented as approved for human use.

What are the limitations of the research on CJC-1295 DAC (5 mg) + Ipamorelin (5 mg) Stack?

Evidence should be interpreted within the population, experimental model, formulation, route, outcome measures, and study design used in each cited source. Preclinical or early-stage findings do not establish clinical efficacy, safety, or approved human use. Where human evidence is available, results should not be generalized beyond the populations and conditions actually studied.

References

[1]
Journal of Clinical Endocrinology & Metabolism — Prolonged stimulation of GH and IGF-I secretion by CJC-1295 in healthy adults
Journal of Clinical Endocrinology & Metabolism
[2]
European Journal of Endocrinology — Ipamorelin, the first selective growth hormone secretagogue
European Journal of Endocrinology
[3]
Endocrine Reviews — Growth hormone secretagogues: mechanisms and clinical applications
Endocrine Reviews
[4]
Sleep Medicine Reviews — Sleep and the GH/IGF-1 axis: physiological and clinical implications
Sleep Medicine Reviews
[5]
Bachem — Handling and storage guidelines for peptides (lyophilized stability)
Bachem
[6]
Bachem — Reconstituted peptide storage and stability recommendations
Bachem
[7]
Translational Andrology and Urology (PMC) — GH secretagogues in body composition management for hypogonadal males
Translational Andrology and Urology (PMC)
[8]
International Journal of Surgery (PubMed) — Ipamorelin for postoperative ileus: tolerability and safety in bowel resection patients
International Journal of Surgery (PubMed)

Additional Research and Background

[1]
Growth Hormone & IGF Research (ScienceDirect) — Ipamorelin induces longitudinal bone growth in rats
Growth Hormone & IGF Research
[2]
Physiological Reviews — The somatotropic axis: GH and IGF-1 regulation and actions
Physiological Reviews
[3]
Clinical Drug Investigation (PMC) — Subcutaneous drug delivery: pharmacokinetic considerations
Clinical Drug Investigation (PMC)

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